Decoding theDynamic Biology of the Brain
Transforming Brain Biology into Blood-Based Insights
through Brain-Derived Circular RNA




Brain disorders are driven by complex, interconnected biological pathways, yet current biomarkers and research approaches remain focused on individual molecular signals, providing only a partial view of disease biology.
Advancing precision neurology begins with a deeper understanding of disease biology. Brain-derived circular RNA (circRNA) provides insight across multiple biological pathways, offering a broader view of the molecular complexity underlying neurological diseases.
Learn About Brain BiologyCircular RNA represents a new molecular layer for investigating the complexity of brain biology.
CircPath™ is our proprietary molecular intelligence platform, translating circular RNA into actionable biological insights.
The platform integrates signals across multiple biological pathways, providing a broader view of neurological disease and enabling new opportunities for neuroscience research.
Designed for academic researchers, biopharma organizations, Alzheimer’s Disease Research Centers, and translational neuroscience programs.
Comprehensive circRNA profiling and pathway-level biological insight.
Identification of A/T biomarker-confirmed Alzheimer’s disease biology.
Prediction of future cognitive impairment and Alzheimer’s disease symptom onset.
CircPath™ is designed to support research across neurodegenerative diseases, with an initial focus on Alzheimer's disease, where there is an urgent need for earlier biological insight and improved biomarkers.
Through CircPath™, Circular Genomics is advancing research applications designed to support disease detection, prediction of Alzheimer's disease (AD) progression to symptom onset, biomarker discovery, and investigation of the biological pathways assocatied with AD etiology and progression.
Our science is built on collaboration with leading researchers and institutions advancing neuroscience.

Foundational discovery of brain-derived circRNA biomarkers and the 34-circRNA Alzheimer's disease signature.


